About Molecular Tumor Genetics

Both germline and somatic genetic alterations play a central role in cancer. Germline mutations, inherited through families, can increase cancer risk and guide screening and prevention strategies. Somatic mutations, acquired in cells over time, drive tumor development and influence how aggressive a cancer is and how it responds to therapy.

Understanding these genetic changes is essential for accurate diagnosis, prognosis, and the selection of targeted treatments. As a result, molecular diagnostic approaches have become a cornerstone of modern oncology, enabling personalized cancer care and improving outcomes for patients.